LIVER LIPIDS IN COMPLETELY DEPANCREATIZED DOGS MAINTAINED WITH INSULIN
نویسندگان
چکیده
منابع مشابه
The Effect of Choline on the Lipid Metabolism of Blood and Liver in the Completely Depancreatized Dog Maintained with Insulin*
Previous studies from thislaboratory (1,2) have shown that pancreas contains two factors active in the lipid metabolism of the depancreatized dog maintained with insulin: (1) a heat-labile blood factor, the ingestion of which causes a rise above normal in all blood lipid constituents, in particular cholesterol; this factor is partially or completely destroyed when pancreas is subjected to autoc...
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Human diabetics on intermediate and long-acting insulin occasionaly become hypoglycemic during exercise. We have shown previously that during exercise, hypoglycemia did not occur in depancreatized insulin-infused dogs because the increments in glucose production and utilization were proportional and of the same magnitude as in normal dogs. Therefore, to elucidate the mechanism of the glucose-lo...
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In normal human subjects the administration of glucose produces an increase in blood pyruvic acid (l-3). In patients with diabetes mellitus the rise in blood pyruvate under the same conditions is either delayed and smaller or does not occur at all (2, 4). Insulin, administered to diabetic patients either simultaneously with glucose or several hours after glucose ingestion, produces a marked inc...
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It was found that dogs with a subcutaneous transplant secreting and discharging pancreatic juice externally absorbed no more fat than dogs in which the pancreatic remnant was undergoing rapid atrophy and sclerosis. Hence, the condition of the pancreatic tissue remaining in the body does not influence the amount of fat absorbed by the intestine. The absorption of fat by the intestinal mucous mem...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1935
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)75324-6